Azinox for dogs: purpose and procedure for use

The composition of this product is selected in such a way as not only to effectively destroy helminths, but also to cleanse the body, stomach and blood of their decay products. This reduces the load on the kidneys and removes toxins, providing an overall healing effect on pets.

general information

The drug is offered in blisters with six or three tablets. The packaging contains all the necessary information about the expiration date, manufacturer, optimal dosages and methods of prevention. The kit also contains instructions with detailed information about the composition of Azinox Plus and how to treat your pet for various types of worms.

The tablets must be stored in a dry place protected from the sun. The shelf life of Azinox is no more than three years from the date of manufacture. On average, the cost of this anthelmintic drug ranges from 15 to 30 rubles per tablet. Azinox Plus is distinguished by its versatility of use. Provided the correct dosage is selected, it is suitable for both very small dogs, including Yorkies, and large shepherd dogs, bulldogs and Rottweilers.

International nonproprietary name

Praziquantel

Group

Medicines used for intestinal helminthiasis

Manufacturers

Agrovetzaschita NVC (Russia)

Instructions for use Azinox plus for dogs: contraindications and dosage of the drug

• Azinox plus for dogs for medicinal purposes is given to animals once in the morning feeding at the rate of one tablet per 10 kg of dog weight.
• For the purpose of prevention, taking the drug in the same dose is repeated quarterly.
• In this case, there is no need to first use laxatives and put the dog on a starvation diet.

If the dog is kept on a sheep flock or farm, it is dewormed every 45 days from December to April and every 30 days from May to November. If the specified dose is observed, no side effects are observed.

However, Azinox Plus for dogs is not recommended for use in puppies under three weeks of age, whelps and lactating bitches after giving birth for 10 days.

When using the drug in accordance with the instructions, no complications or side effects are observed.

But they stop giving the drug to the dog if an allergic reaction occurs or if the animal’s individual sensitivity is increased. The cost of Azinox is about 70-80 rubles per blister with six tablets.

Pharmacological properties and composition

In the instructions for the drug you can find all the necessary information on the composition. This will help you make the right choice of anthelmintic for dogs that are allergic to certain components. The main active ingredients of Azinox are pyrantel pamoate and praziquantel. There are also auxiliary components, including potato starch and lactose.

The principle of action of Azinox is as follows:

• Praziquantel inhibits the enzymes of worms, damages their membrane and causes innervation of the muscles of the helminths. All this leads to paralysis and subsequent rapid death of the parasites. The drug is absorbed by the intestines, its maximum concentration is observed after an hour, and after a day the active component is excreted from the body along with urine.
• Pyrantel is slowly absorbed in the stomach; this component has a pronounced prolonged effect. It prevents helminths from adhering to the intestinal walls, blocks the transmission of motor and nerve impulses of parasites, immobilizes them, leading to the rapid death of worms.

The action of Azinox is based on damage to the outer shell of the parasite and its internal organs. Also, the effectiveness of this drug is achieved due to the destructive effect on the muscle tissue of worms, which quickly die after taking this drug. In helminths, the neuromuscular innervation is blocked, after which the parasites die and are soon eliminated from the body.

Active substances

• praziquantel Rec.INN registered by WHO
• Pyrantel Rec.INN registered by WHO

Release form

Azinox is produced in the form of white tablets with a dividing strip on one side and a logo on the second (a shield located in the center).

Tablets are packaged in blisters of 6 pcs. Their external packaging is a box made of cardboard.

Pharmacological (biological) properties and effects

An anthelmintic drug with cestodocidal action.

Praziquantel has a broad spectrum of anthelmintic action

for all phases of development of tapeworms parasitizing dogs and cats, incl. Echinococcus granulosus, Echinococcus multilocularis, Mesocestoides spp., Taenia spp., Dipylidium caninum and Diphyllobothrium latum.

The mechanism of action of praziquantel is to inhibit the activity of fumarate reductase, disrupt the permeability of cell membranes and muscle innervation, which leads to paralysis and death of the helminth.

Praziquantel is rapidly absorbed from the gastrointestinal tract, the maximum concentration in the blood plasma is reached after 30-60 minutes. It is excreted from the body mainly in urine within 24 hours.

Azinox for dogs and cats, in terms of the degree of impact on the body, is a low-hazard substance (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have embryotoxic, teratogenic or sensitizing effects. Well tolerated by dogs and cats of different breeds and ages.

When is it prescribed?

Azinox tablets for dogs can be prescribed both for the treatment and prevention of helminthiasis. Depending on the purpose of administration, the dosage and frequency of administration are determined. The spectrum of action of the drug is quite wide:

1. Diseases caused by nematodes. The drug is active against roundworms, toxocaras and other representatives of this class.
2. Diseases that cause cestodes. Including diphyllobothriasis, dipylidiasis, taeniasis.

For general prevention of helminthiases, it is sufficient to use only Azinox, since its spectrum of action covers most diseases. Using different anthelmintic drugs at the same time can harm your dog.

Indications for use of Azinox

According to the instructions for Azinox, this drug is used in the following cases:

• Intestinal schistosomiasis;
• Schistosomiasis of the genitourinary system;
• Fasciolopsidosis;
• Trematodosis;
• Opisthorchiasis;
• Paragonimiasis;
• Clonorchiasis;
• Metagonimiasis;
• Teniarinhosa;
• Hymenolepiasis;
• Diphyllobothriasis;
• Teniosis.

Azinox Plus is used for the treatment and prevention of cestodiases and nematodes in dogs, among which are:

• Dipylidiasis;
• Diphyllobothriasis;
• Echinococcosis;
• Mesocestoidosis;
• Taeniasis;
• Uncinariasis;
• Toxocariasis;
• Hookworm;
• Toxascariasis.

Advantages of Azinox

The drug is popular among dog breeders and is widely used in the fight against parasites. It has the following advantages over other anthelmintic drugs:

• suitable for all dog breeds;
• has a wide spectrum of action;
• safe;
• pets tolerate it well;
• the cost of the medicine is low: it can be used quarterly to prevent helminthic infestations without compromising the budget;
• there is no need to adhere to a diet or take laxatives in advance;
• animals take tablets without problems, this is due to the fact that Azinox has a neutral taste;
• There is no need to give the dog medicine in courses; a single dose is enough to achieve the desired result;
• time-tested reliability and maximum efficiency;
• no problems with purchasing (always available in all clinics and veterinary pharmacies).

Indications for use

Azinox tablets are used not only for deworming pets, but can also be taken on a regular basis to prevent the appearance of parasites. It is only necessary to choose the right dose, which will ensure not only its effectiveness, but also complete safety.

Veterinarians prescribe Azinox for the following diseases in dogs:

• Toxocariasis.
• Schistosomiasis.
• Opisthorchiasis.
• Diphyllobothriasis.
• Hydatigerosis.
• Echinococcosis.
• Uncinarium.

A special feature of this drug is its excellent effectiveness not only in the fight against adult helminths, but also against their larvae and eggs. Therefore, it is not necessary to give your pets several tablets at once with a short break in order to initially destroy the worms, and subsequently the young of these parasites that appear. Azinox is versatile, coping with different types of helminths, which is why it is popular with dog owners and is often prescribed by veterinarians.

If the dosage of the drug is selected exactly according to the weight of the pet, then any allergic reactions and side effects are practically excluded.

Side effects

• From the central nervous system - headache, constant feeling of fatigue and drowsiness, confusion, high intracranial pressure, hyperthermia.
• From the digestive system - pain in the abdomen, feeling of nausea, possible vomiting, diarrhea.
• Allergic reactions - rashes, swelling, rarely fever.

It is important! With strict adherence to the treatment regimen, dogs do not experience any side effects.

Dosage and Application

A single dosage for a specific dog is determined at the rate of 1 tablet per 10 kg of weight. Thus:

• if the dog weighs up to 5 kg, half the dose (0.5 tablets) is sufficient;
• if the dog’s weight is 5–10 kg, 1 tablet is prescribed;
• weight 10–20 kg – 2 tablets;
• more than 20 kg – 3 tablets.

The frequency of administration can be determined depending on the purpose for which it is prescribed:

• preventive appointment – ​​once every 3 months;
• admission for therapeutic purposes - once, according to indications (if signs of helminthic infestation are detected).

Before using anthelmintic tablets, there is no need to carry out special cleansing of the intestines (starving the dog or performing cleansing enemas). The product can be taken immediately.

The drug is prescribed in the morning, on an empty stomach. You can mix the crushed tablet into food or force feed it to your dog.

Specifics of taking medication for a dog

When treating parasitic diseases in animals, Azinox plus is given once in the morning, during feeding, the dog takes one tablet per ten kg of its weight. The same dose of medication is used by the dog quarterly if its use is prescribed for preventive purposes.

Azinox pills do not have a pleasant smell or taste. Therefore, in order to make it easier for animals to take the tablet, it is recommended to crush it in a regular plate, add ten milliliters of water, and stir well. Pour the prepared solution into the pet’s mouth using a regular syringe (the needle must be removed).

It is important to strictly follow the dosage of Azinox Plus for dogs, because if it is increased, the animal may experience mild neurological symptoms, vomiting and allergies may also occur. But if used correctly, following the required doses prescribed by the veterinarian, no side effects will bother your pet.

The use of the medicine may depend on the nature of the dog’s illness, then the method of taking Azinox tablets, as well as their dosage, will differ. If your dog is sick with opisthorchiasis, a disease caused by flat parasites from this group, then the drug intake should be increased; the animal is given two tablets at once in a small portion of food. During treatment for this disease, the dog must be kept from eating for about a day.

Doses and order of application.

"Azinox Plus" for dogs is administered orally individually, once, in the morning feeding with a small amount of food, or administered forcibly at a dose of 1 tablet per 10 kg of animal weight.

A preliminary starvation diet and the use of laxatives before deworming animals are not required.

For therapeutic purposes, dogs are dewormed according to indications, for preventive purposes - quarterly in a therapeutic dose.

Farm and poultry dogs are dewormed against causative agents of taeniasis from December to April every 45 days, from May to November - every 30 days.

How it works

The broad antinematode effect is due to two active substances:

1. Praziquantel. Inhibits enzymes, causes innervation of parasite muscles and damages their membrane, which leads to paralysis and death of worms. The substance is quickly absorbed by the intestines, reaches its maximum concentration after an hour, and a day later is completely excreted from the body along with urine.
2. Pirantel. It is slowly absorbed from the gastrointestinal tract and therefore has a prolonged effect. The component prevents helminths from adhering to the intestinal walls: it blocks the transmission of nerve impulses and, subsequently, immobilizes the parasites.

Contraindications and side effects

This drug is quite well tolerated by pets, side effects occur extremely rarely. The only complication described (provided the pills are taken correctly and the instructions are followed) is an allergic reaction.

An allergy occurs when the dog is hypersensitive to the components and can manifest itself in the form of skin rash, itching, and swelling. If this complication occurs, the administration is stopped and desensitizing therapy is prescribed.

If you are lactose intolerant, signs of indigestion may appear, but this is extremely rare.

There are a number of contraindications to the use of Azinox tablets:

1. Pregnancy and first weeks of lactation.
2. Puppies are up to 1 month old.
3. Hypersensitivity to medicinal substances that are part of the drug.
4. Decompensated kidney damage, which is accompanied by a significant impairment of filtration capacity.
5. Liver damage in the stage of decompensation.
6. Acute infectious pathology and exacerbation of chronic diseases are a relative contraindication. You can take this medication after treatment for the underlying disease.

Before the first use, it is better to consult a veterinarian; in the future (for prevention) you can take it yourself.

Analogues of the drug

Azinox Plus does not have an original composition. There are many similar drugs with the same active ingredients. So you can choose a “softer” medication and with a wider spectrum of action. Analogues with prices and descriptions are indicated in the table.

General information about Azinox

“Azinox Plus” is listed as “Praziquantel” in the list of international antihelminthic drugs. The name is given according to the active substance - praziquantel. Additions to it are:

• tetramizole hydrochloride;
• starch;
• glucose.

The drug is available in the form of white or yellowish-gray tablets. The drug is saturated with a characteristic odor. The tablets are packaged in blisters. One blister consists of three or six tablets. It is also packaged in cans of 10, 20, 50, 100 and even 500 pieces.

The period of use is three years. Unused drugs are destroyed. Each package must include instructions from the manufacturer.