Pharmacological properties
Prazitel plus tablets are a combination anthelmintic drug. The combination of praziquantel and pyrantel pamoate included in the drug provides a wide spectrum of anthelmintic action on all phases of development of round and tape helminths parasitizing dogs and puppies, incl. Toxocara canis, Toxocara mystax, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma spp., Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum. The mechanism of action of the active ingredients included in the drug is based on inhibition of fumarate reductase, persistent depolarization of helminth muscle cells, disruption of energy metabolism, which causes paralysis and death of the parasite and promotes its removal from the gastrointestinal tract. When administered orally, praziquantel is quickly absorbed in the intestine and distributed in organs and tissues, and is excreted from the body mainly in the urine in a metabolized form; Pyrantel pamoate is partially absorbed in the intestine and is excreted primarily through urine within 24–48 hours.
In terms of the degree of impact on the body, it is classified as a moderately hazardous substance (hazard class 3 according to GOST 12.1.007-76); in recommended doses it does not have immunotoxic, sensitizing, embryotoxic or teratogenic effects.
Preparation PRAZITEL + for dogs of small and medium breeds antihelm 1 tab per 10 kg 1/2
The price is valid only when placing an order in the online store.
Product availability in the ZooPark retail chain as of: 02/05/2021 18:15:00
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Prazitel plus for dogs and puppies of small and medium breeds, pack. 2 tab.
INSTRUCTIONS
on the use of Prazitel plus ® tablets (Prazitel plus ® tabulettae) for deworming dogs with nematodes and cestodiases
COMPOSITION AND FORM OF RELEASE
Prazitel plus ® in one tablet (0.55 g) contains praziquantel 50 mg, pyrantel pamoate 140 mg, fenbendazole 100 mg as active ingredients, and milk sugar 224.7 mg, potato starch 17.0 mg, calcium as excipients stearic acid 5.8 mg, gelatin 1.5 mg, croscarmellose sodium 11.0 mg. In appearance, the drug is a flat-cylindrical tablet with a chamfer, a score line and the “PR” logo, light yellow in color with a greenish tint. Produced packaged in 2, 4, 6, 8 or 10 tablets in a blister pack made of polyvinyl chloride film and aluminum foil; in contour-free packaging made of polyethylene-coated paper. Outline packages are placed individually in cardboard packs (envelopes) with instructions for use.
PHARMACOLOGICAL PROPERTIES
Prazitel plus® tablets are a combination anthelmintic drug. The combination of praziquantel and pyrantel pamoate included in the drug provides a wide spectrum of anthelmintic action on all phases of development of round and tape helminths parasitizing dogs and puppies, incl. Toxocara canis, Toxocara mystax, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma spp., Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum. The mechanism of action of the active ingredients included in the drug is based on inhibition of fumarate reductase, persistent depolarization of helminth muscle cells, disruption of energy metabolism, which causes paralysis and death of the parasite and promotes its removal from the gastrointestinal tract. When administered orally, praziquantel is quickly absorbed in the intestine and distributed in organs and tissues, and is excreted from the body mainly in the urine in a metabolized form; Pyrantel pamoate is partially absorbed in the intestine and excreted from the body mainly in urine within 24-48 hours. In terms of the degree of impact on the body, Prazitel Plus® tablets are classified as moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76); in recommended doses it does not have immunotoxic, sensitizing, embryotoxic or teratogenic effects.
INDICATIONS
Prazitel plus® tablets are prescribed to dogs and puppies for therapeutic and prophylactic purposes for nematodes (toxocariasis, toxascariasis, uncinariasis, hookworm) and cestodiasis (echinococcosis, alveococcosis, mesocestoidosis, dipylidiasis, diphyllobothriasis) and mixed nematodo-cestodiasis infestations.
CONTRAINDICATIONS
The drug should not be used in animals that are malnourished or sick with infectious diseases, bitches in the first half of pregnancy, or puppies under 2 weeks of age.
DOSES AND METHOD OF APPLICATION
Prazitel plus ® tablets are used for therapeutic and prophylactic purposes individually, once, in the morning feeding with a small amount of food (in a piece of sausage, meat, with minced meat, porridge). If the degree of infestation is high, it is recommended to repeat deworming after 10 days. Dogs for therapeutic and prophylactic purposes are prescribed Prazitel plus ® tablets at a dose of 1 tablet per 10 kg of animal weight. Pregnant bitches are prescribed Prazitel plus ® tablets 3 weeks before giving birth; nursing 2-3 weeks after birth with caution under the supervision of a veterinarian. It is recommended to carry out preventive deworming of dogs once every 3 months, as well as 10 days before vaccination, using the drug in a therapeutic dose. No preliminary fasting diet or use of laxatives is required.
No preliminary fasting diet or use of laxatives is required.
Symptoms that occur during an overdose of the drug have not been established. In case of non-compliance with the established period of repeated treatments, the use of the drug should be resumed in the same dosage according to the same scheme.
SIDE EFFECTS
There are no side effects when using Prazitel plus® tablets in accordance with these instructions. Animals may experience short-term drooling, which resolves spontaneously and does not require the use of medications.
CONTRAINDICATIONS
Individual intolerance to the components of the drug is possible. Prazitel plus® tablets should not be used concomitantly with anthelmintics containing piperazine. Prazitel Plus® tablets are not intended for use in food producing animals.
SPECIAL INSTRUCTIONS
No specific effects of the drug upon first administration or upon its discontinuation have been identified.
Personal prevention measures . When working with Prazitel Plus® tablets, you should follow the general rules of personal hygiene and safety precautions provided for when working with medications. When finished, wash your hands thoroughly with warm water and soap. In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water. People with 3 hypersensitivity to the components of the drug should avoid direct contact with Prazitel Plus®. If allergic reactions occur or if the drug accidentally enters the human body, you should immediately contact a medical facility (bring with you the instructions for use of the drug or the label). Empty drug packaging must not be used for household purposes; they must be disposed of with household waste.
STORAGE CONDITIONS
Store Prazitel plus® tablets in the manufacturer's sealed packaging, in a dry place, protected from direct sunlight, separately from food and feed, at a temperature from minus 10 C to 25 C. 5. Prazitel plus® tablets should be stored in places inaccessible to children. The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of production. Prazitel plus® tablets should not be used after the expiration date. Unused medicinal product is disposed of in accordance with legal requirements.
Directions for use and doses
Prazitel plus tablets are used for therapeutic and prophylactic purposes individually, once, in the morning feeding with a small amount of food (in a piece of sausage, meat, with minced meat, porridge). If the degree of infestation is high, it is recommended to repeat deworming after 10 days.
- Dogs for therapeutic and prophylactic purposes are prescribed tablets at a dose of 1 tablet per 10 kg of animal weight.
- Pregnant bitches are prescribed 3 weeks before giving birth; nursing - 2-3 weeks after birth with caution under the supervision of a veterinarian.
- It is recommended to carry out preventive deworming of dogs once every 3 months, as well as 10 days before vaccination, using the drug in a therapeutic dose.
No preliminary fasting diet or use of laxatives is required.
Prazitel tablets for dogs
Just like the suspension, this variation of the drug is available in two forms:
- "Prasitel Plus" This medicine can be used for four-legged animals of different body weights and different ages (not earlier than two weeks of age). One tablet of the drug contains the same concentration of active components as the suspension for adults - the maximum amount. As for the excipients, these are starch, milk sugar, gelatin.
- "Prasitel" for puppies and cats. This type of tablet has a more gentle composition, so it is most often recommended for use for children. There is no fenbendazole, and the remaining active ingredients are the same as in the puppy suspension. The auxiliary components are the same as in the previous type of tablets.
One box of tablets contains from 2 to 10 pieces. This packaging allows you not to overpay for excess items, which will then simply go in the trash. In addition to the tablets, the box contains detailed instructions.
Personal prevention measures
- When working with Prazitel plus tablets, you should follow the general rules of personal hygiene and safety precautions provided for when working with medications.
- When finished, wash your hands thoroughly with warm water and soap.
- In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water.
- People with hypersensitivity to the components of the drug should avoid direct contact with it.
- If allergic reactions occur or if the drug accidentally enters the human body, you should immediately contact a medical facility (bring with you the instructions for use of the drug or the label).
- Empty drug packaging must not be used for household purposes; they must be disposed of with household waste.
Indications for use
A drug is prescribed for the treatment of:
- nematodes that occur due to roundworms;
- opisthorchiasis;
- cestodoses that appear as a result of infection with tapeworms and their vital activity;
- mixed invasions.
The drug is used not only for treatment, but also as a prevention of infection. To protect your pet, you need to give him an anthelmintic quarterly, as well as additionally before mating and before vaccination.
Description of the mechanism of action
The components of the drug affect the permeability of the parasite's cell membranes. As a result, the process of transmission of nerve impulses is disrupted in helminths. Some of the worms die, the rest are paralyzed. Unable to gain a foothold, they leave the body during bowel movements.
Prasicite is a broad-spectrum anthelmintic. It effectively destroys the following parasites:
- nematodes;
- cestodes;
- insects;
- ticks.
By following the dosage specified in the instructions for use, you can be confident that the drug is safe for the skin and mucous membrane of your pet’s gastrointestinal tract.
Dosage for treatment and prevention
Prazicide in tablet form is used for dogs of any size. 1 tablet is designed for 10 kg of live weight. Therefore, for large breeds, calculating the dosage is very simple. The pills are crushed into powder and mixed with the morning meal. For small dogs, they are broken along the cutting line, and the rest is wrapped in paper, signed and the expiration date indicated.
Prazicide in the form of a suspension is available in three versions. The packages show different pictures and certain numbers are written in large letters:
- 20 – for small breed puppies (1kg – 1ml);
- 40 – babies of medium and large pets (2 kg - 1 ml);
- 60 – adult pets (3 kg – 1 ml).
Prazicide in the form of drops is also made in several varieties: for dogs weighing less than 5 kg, 5-10 kg, 10-20 kg, 20-30 kg. Using the drug is not difficult. With his left hand, the owner spreads the dog’s fur at the withers, and with his right hand he squeezes the entire contents of the pipette onto the skin. It is not necessary to rub in the medicine.
If the owner finds fleas on the fur or helminths in the feces, the drug is given twice with a break of 10 days. During this period, adult parasites develop from eggs (which are more difficult to destroy). A preventive appointment is carried out once every four months, and also before vaccination injections. In this case, a repeat procedure is not necessary.
