Dehinel Plus anthelmintic for dogs, pack. 12 and 60 tab.

Compound

The drug contains 3 substances: febantel, pyrantel embonate and praziquantel .

Febantel belongs to the category of polybenzimidazoles, which are active against the destructive effects of Toxascaris, Uncinaria, Ancylostoma, Trichocephalus and Toxocara.

The mechanism of action of the drug is to disrupt the microtubular function of nematodes, as well as to suspend the synthesis of the tubulin protein. In this way, a lasting effect is achieved, which is accompanied by the rapid death of helminths.

Pyrantel embonate belongs to the category of pyrimidines. In sensitive helminths, it blocks neuromuscular transmission like depolarizing muscle relaxants, causes persistent depolarization and spastic paralysis of the muscles, and ensures the removal of worms from the body.

Highly active against invasions caused by pinworms and roundworms.

Praziquantel is a pyrazine isoquinoline derivative. Increases the permeability of helminth cell membranes for calcium ions, causing a generalized contraction of the parasite's muscles, which turns into persistent paralysis, leading to the death of the helminth.

Composition and action

A wide range of applications is provided by a complex of three active components. The basis is:

• pyrantel;
• praziquantel;
• febantel.

In this combination, the medicine is most effective against cestodes and nematodes that parasitize the gastrointestinal tract.

Pyrantela pamoate

– a substance active against various types of nematodes. The action is aimed at blocking nerve impulses in parasites, which causes paralysis, and the helminths die. The substance has a prolonged effect.

Febantel

– active against nematodes of various genera. As a result, glucose is not absorbed in the helminth's body, which leads to cell destruction and causes the death of the worm.

Praziquantel

– a substance that actively destroys cestodes. Due to its effect, energy metabolism in the parasite’s body is disrupted, which causes paralysis and subsequent death. Praziquantel begins to act quickly, reaching its maximum concentration in the animal’s blood plasma within 1-3 hours.

Important! Dehinel Plus can be used both for the treatment and prevention of helminth infection.

Instructions for use

Dosage by weight

The dose of the drug is measured at the rate of 1 tablet. per 10 kg of live weight.

Tablets are given orally once during morning feeding. The use of this medicine does not require dieting or the use of laxatives.

For therapeutic purposes, the drug is given according to indications, for preventive purposes - every quarter. In case of severe infestation, the drug is given twice with an interval of 2 weeks.

How to give?

There are several clever ways to get your dog to swallow a pill:

1. Place the tablet in food and give it to the animal.
2. Place the medicine on the back of the tongue, close the dog's mouth and stroke its throat until it swallows the tablet.
3. If your pet is trained to catch treats, you can try throwing a treat, a pill, and another treat.
4. The tablet can be crushed, mixed with a small portion of canned dog food (it’s best to make a cake, pour the powder inside, roll it into a ball and give it to the dog).

No matter how the medicine is given, the tablet should not be heated, otherwise chemical changes may occur in it and it will not give the desired effect.

Anthelmintic for dogs KRKA Dekhinel Plus No. 10 with meat flavor 1 tablet.

The price is for 1 tablet. Dekhinel Plus tablets with meat flavor for the treatment and prevention of helminthiasis in dogs

COMPOSITION AND RELEASE FORM Anthelmintic drug for dogs Dehinel Plus (international nonproprietary name: febantel + pyrantel embonate + praziquantel) contains as active ingredients in one tablet: 150 mg of febantel, 144 mg of pyrantel embonate and 50 mg of praziquantel, and as auxiliary components - lactose monohydrate, corn starch, povidone K30, sodium lauryl sulfate, microcrystalline cellulose, colloidal silicon anhydride, magnesium stearate and meat flavoring. Dehinel Plus are round tablets, weighing 658 mg for oral use, yellow in color with dark inclusions with beveled edges and a cross-shaped notch on one side. The drug is packaged in blisters of 10 tablets, which are placed in cardboard boxes.

PHARMACOLOGICAL PROPERTIES Dehinel Plus, thanks to its active ingredients, has antiparasitic activity against cestodes: Echinococcus granulosus, Echinococcus multilocularis, Mesocestoides lineatus, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp. and nematodes: Toxocara canis, Toxascaris leonina, Uncinaria spp., Ancylostoma spp., Trichuris vulpis. Febantel, moderately absorbed from the gastrointestinal tract, causes inhibition of tubulin protein synthesis and glucose supply in nematodes, and simultaneously inhibits fumarate reductase, an enzyme responsible for the energy metabolism of helminths. Pyrantel embonate is very poorly absorbed when administered orally and therefore exerts its effect directly on the surface of the mucous membrane of the gastrointestinal tract of a sick dog. It blocks neuromuscular impulse transmission in nematodes and causes paralysis of the helminth muscles, so the parasites are easily removed from the host’s gastrointestinal tract. Praziquantel is well absorbed in the gastrointestinal tract and has a detrimental effect on cestodes (tapeworms) by increasing the permeability of parasite cell membranes to calcium ions and inhibiting fumarate reductase, which causes spastic contraction of the parasite's muscles, turning into paralysis. Praziquantel is excreted unchanged in the bile. Dehinel Plus, in terms of the degree of impact on the body of warm-blooded animals, is a low-hazard substance and in recommended doses does not have a sensitizing or hepatotoxic effect.

APPLICATION Prescribed to dogs for prophylactic and therapeutic purposes for nematodes (toxocariasis, toxascariasis, uncinariasis, hookworm disease, trichocephalosis) and cestodiasis (tenidosis, dipylidiasis, echinococcosis, diphyllobothriasis, mesocestodiasis).

DOSES AND METHOD OF APPLICATION Dehinel Plus is administered to dogs individually orally, once in the morning feeding at the rate of 1 tablet per 10 kg of animal weight. Before using the drug, a fasting diet and the use of laxatives are not required. In cases of intensive helminth infection, animals are recommended to re-use the drug after 14 days at the same dose. For therapeutic purposes, animals are given the drug according to indications, and for prophylactic purposes - quarterly (once every 3 months) in a therapeutic dose. No symptoms of overdose have been identified in dogs. The specific effects of the drug upon its first use have not been established.

PREVENTIVE TREATMENT REGIME Puppies: at the age of 4, 6 and 12 weeks.
Young dogs: every 2–3 months until 1 year of age. Adult dogs: 3-4 times a year. Bitches: during heat, two weeks before giving birth and 2 weeks after giving birth. All dogs: before vaccination. SIDE EFFECTS There are, as a rule, no side effects or complications when using Dehinel Plus in accordance with these instructions. In sensitive animals, in rare cases, individual signs of intolerance to the components of the drug are possible. If allergic reactions occur, use of Dehinel Plus is stopped and desensitizing therapy is carried out.

CONTRAINDICATIONS Increased individual sensitivity to the components of the drug. The use of the drug is not allowed for puppies in the first three weeks of life and for female dogs in the first two-thirds of pregnancy. It is not allowed to prescribe Dehinel Plus simultaneously with piperazine derivatives, levamisole, organophosphorus compounds and other drugs that have a cholinergic effect.

SPECIAL INSTRUCTIONS Not required when using the drug.

STORAGE CONDITIONS In sealed manufacturer's packaging, in a dry place, protected from direct sunlight and inaccessible to children and animals, separately from food and feed at a temperature of 0°C to 30°C. Shelf life in unopened packaging, subject to storage conditions, is 3 years from the date of manufacture.

Side effects

Negative effects or complications after using the medicine have not been established.

Overdose may cause side effects such as:

• strong thirst;
• weakness;
• dysfunctions of the gastrointestinal tract.

In this case, it is necessary to rinse the stomach.

If you are hypersensitive to the components of the medication, allergic reactions may occur. In this case, the pills are stopped and rehabilitation therapy is carried out.

Reviews

Owners

German, 42 years old, Nizhny Novgorod:

“When we moved into our house, our German shepherd settled outside in an enclosure. For this reason, the issue of preventing helminthic infestations arose. As prescribed by the doctor, we bought Dehinel Plus XL. The dog eats the tablet without any problems due to the pronounced meaty smell. We have been using the drug for more than 2 years, there have been no negative consequences. No worms were found during regular examinations.”

Vera, 45 years old, Volgograd:

“We regularly prevent helminthic infestations with the drug Dehinel Plus in our Beagle. Before this, we used Drontal for some time; To avoid addiction, we decided to switch to another medicine, the doctor advised Dekhinel. Have used it several times already, no side effects. We'll buy it for now."

Veterinarians

Artem, 42 years old, veterinarian, Moscow:

“Dehinel is an effective drug from a trusted manufacturer, has a wide spectrum of action against different types of parasites. To avoid negative consequences, you must follow the dosage indicated in the instructions.”

Maria, 33 years old, veterinarian, St. Petersburg:

“I consider Dehinel Plus to be an effective but toxic antiparasitic agent. Incorrect dosage can cause severe liver dysfunction. For this reason, before using the medicine, you should always consult a doctor so that he can accurately calculate the dose and promptly identify possible contraindications.”

How to fight parasites/roundworms in cats?

For periodic prevention of roundworms and other types of parasites for cats, I change medications. I already wrote about drops for the withers “Drops for cats Helmintal K Ecoprom”, but experts advise replacing medications so that there is no addiction and there is an effective effect.

Front side of the package

In the online store I once again found an imported drug in the form of two tablets called “Dehinel® Cats” (Slovenija/Slovenia, the developer of the combined anthelmintic drug is a corporation (KRKA, dd, Novo mesto).

The price is about the same as Helmintal. In this store I get free delivery and bonuses, it’s profitable to buy from them)

Information on packaging

I will not list the entire composition with fillers, but the main active ingredients are pyrantel embonate, the content of which in one tablet is 230 mg and praziquantel, respectively, 20 mg per tablet.

Pills

Packaged very well, the foil plate allows you to hermetically preserve the drug itself. The tablets themselves have a biconvex shape, with a line marked in the middle for ease of division, since the full dosage is not always required; the weight of the animal should be taken into account.

Dose of tablets

In my case, the cat is an adult, of average size up to four kilograms, so I immediately took the whole tablet. You can give it to the root of the tongue, but it’s difficult for me to cope with her alone, and I don’t want to torture the animal, she gets very scared, I feel sorry for her.

If you forcefully push it onto the root of your tongue, you might even spit out the pill, since you have to know how to push it far. I chose to crush the tablet into powder and add it to a treat.

Info

At the same time, I did not feed the cat; I first kept her hungry during the day so that she could “work up” her appetite, otherwise the full dosage would not be obtained if the appropriate dose of the drug was not included in the food. It is better to use the drug in the morning on an empty stomach and the advantage is that no laxatives are required medications for your pet.

Instructions

After the procedure, I did not notice any side effects, the pet’s behavior did not change. I was satisfied with everything, but for prevention, the manufacturer recommends repeating it after a while and consolidating the effect with a second tablet, and carrying out prevention quarterly. I hope that the action will last for several months, the cat does not go outside, it is indoors. Then we will think about changing the drug again.

Instructions

I recommend Dehinel for cats as a reliable and new drug for the frequency of changing anthelmintics.

Instructions

Analogs

An analogue in composition is the drug Drontal Plus for dogs. The medication is available in several forms: tablets and suspension. Unlike Dehinel Plus, Drontal Plus tablets can be given from the second month of pregnancy, and to puppies - from 6 months (suspension - from 3 weeks). The cost of this medication is higher.

A cheaper analogue of Dekhinel Plus is the anthelmintic Pratel . In addition, this drug has a lower dosage and low weight. The disadvantages include the fact that it does not contain febantel, so its effectiveness may be slightly lower.

Dehinel Plus For Large Breed Dogs Weight 2310 mg 1 tab (1*12)

COMPOSITION AND FORM OF RELEASE

Anthelmintic drug for dogs Dehinel Plus (international nonproprietary name: febantel + pyrantel embonate + praziquantel) contains as active ingredients in one tablet: 525 mg of febantel, 504 mg of pyrantel embonate and 175 mg of praziquantel, and as auxiliary components - lactose monohydrate, corn starch, povidone K30, sodium lauryl sulfate, microcrystalline cellulose, colloidal silicon anhydride and magnesium stearate. Dehinel Plus are round tablets, weighing 2310 mg for oral use, yellow in color with dark inclusions with beveled edges and a cross-shaped notch on one side. The drug is packaged in blisters of 6 tablets, which are placed in cardboard boxes.

PHARMACOLOGICAL PROPERTIES

Dehinel Plus, thanks to its active ingredients, has antiparasitic activity against cestodes: Echinococcus granulosus, Echinococcus multilocularis, Mesocestoides lineatus, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp. and nematodes: Toxocara canis, Toxascaris leonina, Uncinaria spp., Ancylostoma spp., Trichuris vulpis. Febantel, moderately absorbed from the gastrointestinal tract, causes inhibition of tubulin protein synthesis and glucose supply in nematodes, and simultaneously inhibits fumarate reductase, an enzyme responsible for the energy metabolism of helminths. Pyrantel embonate is very poorly absorbed when administered orally and therefore exerts its effect directly on the surface of the mucous membrane of the gastrointestinal tract of a sick dog. It blocks neuromuscular impulse transmission in nematodes and causes paralysis of the helminth muscles, so the parasites are easily removed from the host’s gastrointestinal tract. Praziquantel is well absorbed in the gastrointestinal tract and has a detrimental effect on cestodes (tapeworms) by increasing the permeability of parasite cell membranes to calcium ions and inhibiting fumarate reductase, which causes spastic contraction of the parasite's muscles, turning into paralysis. Praziquantel is excreted unchanged in the bile. Dehinel Plus, in terms of the degree of impact on the body of warm-blooded animals, is a low-hazard substance and in recommended doses does not have a sensitizing or hepatotoxic effect.

APPLICATION

Prescribed to dogs for prophylactic and therapeutic purposes for nematodes (toxocariasis, toxascariasis, uncinariasis, hookworm disease, trichocephalosis) and cestodiasis (tenidosis, dipylidiasis, echinococcosis, diphyllobothriasis, mesocestodiasis).

DOSES AND METHOD OF APPLICATION

Dehinel Plus is administered to dogs individually orally, once in the morning feeding at the rate of 1 tablet per 35 kg of animal weight.

Before using the drug, a fasting diet and the use of laxatives are not required. In cases of intensive helminth infection, animals are recommended to re-use the drug after 14 days at the same dose. For therapeutic purposes, animals are given the drug according to indications, and for prophylactic purposes - quarterly (once every 3 months) in a therapeutic dose.

No symptoms of overdose have been identified in dogs.

The specific effects of the drug upon its first use have not been established.

PREVENTIVE TREATMENT REGIME

Puppies: 4, 6 and 12 weeks of age.

Young dogs: every 2–3 months until 1 year of age.

Adult dogs: 3-4 times a year.

Bitches: during heat, two weeks before giving birth and 2 weeks after giving birth.

All dogs: before vaccination.

SIDE EFFECTS

As a rule, there are no side effects or complications when using Dekhinela Plus in accordance with these instructions.

In sensitive animals, in rare cases, individual signs of intolerance to the components of the drug are possible. If allergic reactions occur, use of Dehinel Plus is stopped and desensitizing therapy is carried out.

CONTRAINDICATIONS

Increased individual sensitivity to the components of the drug. The use of the drug is not allowed for puppies in the first three weeks of life and for female dogs in the first two-thirds of pregnancy.

It is not allowed to prescribe Dehinel Plus simultaneously with piperazine derivatives, levamisole, organophosphorus compounds and other drugs that have a cholinergic effect.

SPECIAL INSTRUCTIONS

When using the drug are not required.

STORAGE CONDITIONS

In sealed manufacturer's packaging, in a dry place, protected from direct sunlight and inaccessible to children and animals, separately from food and feed at a temperature of 0°C to 30°C. Shelf life in unopened packaging, subject to storage conditions, is 3 years from the date of manufacture.