Anthelmintic for cats Apicenna Prazicide Suspension Plus 1 ml/1 kg, syringe dispenser at mirkorma.ru

Composition and release form

The active substances in the suspension are the following:

praziquantel has a detrimental effect on tapeworms and roundworms;
pyrantel pamoate destroys parasites and cleanses the body of toxins (waste products of parasites);
febantel has a fatal effect on intestinal helminths (included only in Prazicide Plus).

The composition also includes excipients, including purified water, glycerin, flavoring, sweetener, etc.

The medicine is produced in the form of a liquid with a yellowish tint. It does not have a strong odor and has a pleasant sweet taste (as indicated in the instructions), so animals consume it without problems. The suspension is packaged in polymer bottles that are screwed on with a cap. Equipped with child protection. The volume of bottles varies from 5 to 15 ml. Each package of the drug comes with instructions and a dosing syringe, which greatly simplifies measuring the required amount of medicine.

Depending on the concentration and ratio of active ingredients, the medicine is available in several versions:

1 ml of Prazicide 20 contains 5 mg of praziquantel and 15 mg of pyrantel pamoate. Designed for small breed puppies.
Prazicide 40 contains 10 mg of praziquantel and 30 mg of pyrantel pamoate per milligram of medicinal liquid. Suitable for large and medium sized puppies and small breed pets.
Prazicide 60 is suitable for adult dogs, including large breeds. 1 ml of the drug contains 15 mg of prazikantel and 45 mg of pyrantel pamoate.
Prazicide Plus is different in that it also contains febantel. Contains 15 mg of praziquantel, 45 mg of febantel and pyrantel pamoate. Can be used for adults and large breed puppies.

When purchasing a drug, you should pay attention to the concentration of active substances and purpose.

Description

Prazicide suspension Plus 7 ml for oral use for adult cats. As active ingredients, 1 ml contains: 15 mg of pyrantel pamoate, 15 mg of febantel, 1.5 mg of praziquantel and excipients: polyvinylpyrrolidone - 10 mg, glycerin - 50 mg, aspasvit Ts-200 - 5 mg, Tween-80 - 6 mg, xanthan gum – 3 mg, sodium benzoate – 1.5 mg, potassium sorbate – 1.5 mg, antifoam – 0.7 mg, citric acid – 0.5 mg, “Milk chocolate” flavor – 1 mg, Na- carboxymethylcellulose – 3 mg, sucralose – 1 mg, β-cyclodextrin – 5 mg and purified water – up to 1 ml. In appearance, the drug is a light yellow suspension; during storage, separation of the suspension is allowed, which disappears when shaken.

Pharmacological properties

The medicine is effectively used against various types of worms that parasitize the gastrointestinal tract. The wide spectrum of action of the drug is achieved due to the complex effect of active substances:

Praziquantel has a negative effect on cestodes. Due to increased permeability of cell membranes, the transmission of nerve impulses is disrupted. Subsequently, metabolic processes are disrupted, paralysis and death of parasites occurs. The substance affects sexually mature helminths, as well as their larvae and eggs. Helps cleanse the body of worms by removing them out.
Pyrantel pamoate acts on various types of nematodes. Blocks the transmission of nerve impulses, which ultimately leads to the death of parasites.
Febantel prevents the absorption of glucose by parasites and the production of tubulin, which causes the death of helminths.

Praziquantel is absorbed into the blood through the gastrointestinal tract in a short period of time. After just a couple of hours, the concentration of the substance in the blood plasma reaches its maximum value. It is eliminated from the body within a day. But pyrantel pamoate is absorbed and excreted for a long time, which ensures the effectiveness of the drug for several months.

How it works and when to use it

Regardless of the form of release, the medication contains components that lead to disruption of the transmission of nerve impulses due to changes at the cellular level. As a result, the parasites suffer from paralysis and then die. The main feature that determines the effectiveness of the drug is that the medicine affects parasites at all stages of development, including eggs and larvae.

Tablets and suspension are used to treat and prevent:

nematodes;
cestodiasis;
mixed invasions.

The drug is effective against all known types of roundworms and tapeworms. Prazicide complex (drops) has a wider spectrum of action, as it destroys not only internal, but also external parasites. It is also used to get rid of fleas, lice, ticks and other ectoparasites, as well as to prevent their occurrence.

The instructions for use indicate that the use of the drug in recommended doses is not dangerous for cats, but before using Prazicide you should consult a doctor.

Indications for use

Prazicide plus suspension is prescribed to dogs of small and large breeds for treatment of parasites in the gastrointestinal tract:

with uncinariasis;
with toxocariasis;
with hookworm;
with toxascariasis;
with dipylidia;
with taeniasis;
with trichocephalosis;
with diphyllobithrosis;
with mesocestoidosis, etc.

It is also used for the treatment of mixed helminthic infestations. In addition, the medicine is suitable for prophylactic purposes, that is, preventing infection with internal parasites. The drug can also be used for deworming before vaccination.

Dosages

Dosages are calculated taking into account the age of pets and their weight category. If a suspension is chosen as a medicine, then 1 ml of the drug will be required per 1 kg of the cat’s body weight, which is very convenient to measure with a dispenser syringe.

Prazicide tablets are taken per 3 kg of cat weight - one tablet

Drops are also calculated by weight: if the cat weighs less than 5 kg, then you need to take 0.85 ml of the product, that is, one pipette. If this threshold is exceeded, 2 pipettes are already used, that is, 1.7 ml.

Instructions for use

When using an anthelmintic drug, the dose must be calculated based on the concentration of active substances and the weight of the animal:

For puppies of small breeds, Prazicide 20 should be used. For every kilogram of weight, 1 ml of the drug is needed.
For small and medium-sized pets, as well as large breed puppies, it is best to use Prazicide 40. The dose should be calculated based on the fact that 1 ml of medication will be needed per 2 kilograms of weight.
For dogs of any size it is worth using Prazicide 60 or plus. When calculating the dose per 3 kg of pet weight, take 1 ml of liquid.

The instructions for use indicate that a number of simple recommendations must be followed when using Prazicide suspension for dogs:

If the drug is used for treatment, it is given to pets once. For severe or mixed infestations, the procedure is repeated after 10 days.
If the medicine is used for prophylaxis, the dose should be repeated every three months.
Use the medicine in the morning. It can be mixed with a small amount of food or injected forcibly onto the root of the tongue so that the pet cannot spit it out.
Before measuring the medicine with a dispenser, it is necessary to shake the bottle well, since the suspension tends to separate during long-term storage.
Before using the anthelmintic, no preparatory procedures are required. The dog does not need to be kept on a diet or given an enema.

Anthelmintic for cats Apicenna Prazicide Suspension Plus 1 ml/1 kg, syringe dispenser

Properties

Prazicide suspension 60, 40, 20 belongs to combined anthelmintic drugs. The drug has a wide spectrum of anthelmintic effect on all phases of development of round and tape helminths parasitizing dogs and cats, including Tohocara canis, Toxocara mistax, Toxascaris leonina, Uncinaria stenocephala, Trichuris vulpis, Ancylostoma caninum, Echinococcus granulosus, Alveococus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobotrium latum, Multiceps multiceps.

The mechanism of action of praziquantel and pyrantel, which are part of the drug, is based on inhibition of fumarate reductase, persistent depolarization of helminth muscle cells, disruption of energy metabolism, which causes paralysis and death of helminths and promotes their removal from the gastrointestinal tract.

When the drug is administered orally, praziquantel is rapidly absorbed from the gastrointestinal tract, reaching its maximum concentration in the blood plasma after 1-3 hours, and is distributed in the organs and tissues of the animal; excreted from the body mainly in urine (up to 80%) within 24 hours. Pyrantel pamoate is poorly absorbed, which ensures its prolonged effect on helminths in the intestines; excreted from the body mainly unchanged in feces (93%).

Prazicide suspension 60, 40, 20 in terms of the degree of impact on the body is classified as a low-hazard substance (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have embryotoxic, teratogenic or sensitizing effects. Well tolerated by dogs and cats of different breeds and ages.

Indications

Prazicide-suspension 60, 40, 20 is prescribed to adult dogs and cats, puppies and kittens from 3 weeks of age for prophylactic and therapeutic purposes for nematodes (toxocariasis, toxascariasis, uncinariasis, trichucephalosis, hookworm infection), cestodiasis (taeniosis, dipylidiasis, echinococcosis, diphyllobothriasis , mesocestoidosis) and mixed nematodo-cestodal infestations.

Dosage and method of administration

Prazicide-sweet suspension is administered to animals individually, ONCE for therapeutic and prophylactic purposes, in the morning feeding with a small amount of food or administered forcibly using a dispenser syringe at the rate of:

type of drug prazicide-suspension 60, 40, 20	quantity drug	body mass animal
for cats	1 ml	1 kg
for kittens	1 ml	1 kg
for dogs	1 ml	3 kg
for small breed puppies	1 ml	1 kg
for puppies of medium and large breeds	1 ml	2 kg

BEFORE USE, THE BOTTLE WITH THE PREPARATION MUST BE SHAKED CAREFULLY FOR 1-2 MINUTES! No preliminary fasting diet or use of laxatives is required. In case of severe infestation, deworming is recommended to be repeated after 10 days.

For preventive purposes, deworming is carried out quarterly, as well as before each vaccination. For pregnant females, the drug is prescribed 3 weeks before the expected birth with caution, under the supervision of a veterinarian, for lactating females - 2-3 weeks after birth.

Side effect

When Prazicide-suspension 60, 40, 20 is used in accordance with these instructions, side effects and complications in animals, as a rule, are not observed. In case of increased individual sensitivity to the components of the drug and the appearance of allergic reactions, its use is stopped and the animal is prescribed antihistamines and symptomatic drugs.

Contraindications and side effects

If the recommended doses are followed, Prazicide suspension is considered safe for dogs, but in some cases it is better to avoid using it. It is necessary to postpone the appointment in the following cases:

puppies up to 3 weeks old;
infectious diseases;
postoperative period;
individual intolerance to the components included in the composition.

It is not recommended to use the medicine for weakened animals. Pregnant bitches are not given the suspension 3 weeks before giving birth and 14-20 days after giving birth. During the rest of pregnancy and lactation period, use after consultation with a veterinarian.

If the dose is exceeded, the following phenomena may be observed:

increased salivation;
diarrhea, vomiting and other gastrointestinal disorders;
lethargy;
refusal of food;
oppression.

It is necessary to take measures to quickly remove the drug from the body and consult a doctor.

If you do not exceed the dose, side effects do not occur. Sometimes allergic reactions occur. They can manifest themselves in the form of rashes, itching and other symptoms. In this case, the medicine is no longer used; the pet is prescribed antihistamines and medications to relieve symptoms.

The anthelmintic should not be used together with medications containing piperazine.

special instructions

In case of an overdose of the drug, the animal may experience a depressed state, refusal to feed, excessive salivation, and gastrointestinal upset. In these cases, enterosorbents and symptomatic therapy are used.

When using the drug for the first time in cats, self-limiting hypersalivation is possible.

Disturbances in the deworming regimen should be avoided as this may result in decreased effectiveness. If the next dose is missed, the drug must be administered as soon as possible in the same dose, then the interval between administrations of the drug does not change.

Precautions and storage

When working with a veterinarian, simple precautions should be followed. During the procedure you should not drink, eat or smoke. After the medicine is given to the animal, you need to wash your hands. People who have increased sensitivity need to be especially careful. Components of the composition may cause an allergic reaction.

During storage, the following conditions must be observed:

temperature range from 0 to 25°C;
lack of ultraviolet radiation and sun;
dry place.

The medication should not be stored near food or feed. Children should not have access to the storage area.

Owner reviews

Irina, Chihuahua owner:

“I know very well how important it is to carry out deworming on time, especially if there is a child in the house. I have been using Prazicide suspension for my dogs since they were two months old. I am very pleased with the drug. It does its job well, but the most important thing is that it’s easy to measure the right amount. Owners of small dogs will understand me. Recommended for owners of pets of large and small breeds.”

Victoria, Pekingese owner:

“We have been using this suspension for a long time, we have been tested several times - no worms were found. Among the advantages, I would like to note the affordable price and convenient form of the drug. The fact is that my Quince categorically refuses to take pills. If you really insist, she may chew them a little, but then she will still spit them out. With a suspension of such problems. I mixed it with food and the dog gobbled it up for his dear soul.”